CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, or other conditions that are Aliases: MUC16, CA125, mucin 16, cell surface associated. The CA-125 blood test can spot proteins made by ovarian cancer, but it doesn’t always mean you have cancer. WebMD explains why and when the test is used and what your results may mean.
Feb 07, 2018 · Read about CA 125, a test used to determine levels of a tumor marker that may be elevated in cases of ovarian cancer. Certain benign conditions, including endometriosis, uterine fibroids, and pelvic inflammatory disease, may be associated with increased CA 125 results. Learn about normal values for CA 125. Elevated CA125 in breast cancer--A sign of advanced disease. Norum LF(1), Erikstein B, Nustad K. Author information: (1)Central Laboratory, Norwegian Radium Hospital, Oslo, Norway. The serum tumor markers CA 125, MUC1 and CEA were measured in 221 breast cancer patients over a period of 2 years.Cited by: 67.
Aug 08, 2019 · One of the least mentioned reasons for elevated CA-125 is the effects of drugs used to treat breast cancer and other cancers. Another often unmentioned cause of variable levels is peri-menopause. All this being said, if it would make you feel better to have the ovaries removed, I . Cancer Antigen 125 (CA-125) is a tumor marker primarily used to monitor treatment of ovarian cancer and to detect whether cancer has come back after treatment is complete. Sometimes CA-125 may be ordered to help detect early ovarian cancer in women at high risk (e.g., BRCA mutation) or to help investigate a lump in a woman’s lower abdominal area (pelvic mass).
The retrospective analysis of 250 breast cancer patients with disseminated disease provided evidence that the increase in CA 125 serum levels in these patients was caused by lung metastases or pleural effusions. Seven patients with lung metastases and pleural involvement had elevated CA 125 levels Cited by: 8. Cancer antigen 125 (CA-125) is a protein found in ovarian cancer cells. A CA-125 blood test measures the amount of cancer antigen 125 in the bloodstream. The protein is produced by the cells and Author: Darla Burke.
For these reasons, doctors don't recommend CA 125 testing in women with an average risk of ovarian cancer. Women with a high risk of ovarian cancer, such as those with mutations in the BRCA1 and BRCA2 genes, which increase the risk of breast and ovarian .